Physiology is the most dynamic of all biological disciplines as it is the study of function.
In order to better understand both healthy and pathological function in living systems it is essential to characterize the important system components across all levels of biological organization (from molecule to organ) as they interact with one another over time.
Faculty in this Area of Excellence develop and apply sophisticated methods for facilitating the study of key dynamic events underlying physiological function.
Experiments are performed both in vivo and ex vivo utilizing an array of powerful model organisms (e.g. mouse, frog, zebrafish).
This group makes heavy use of electrophysiology, telemetry of implanted sensors in conscious animals, ultrasound as well as powerful pulmonary, renal and cardiovascular phenotyping facilities (e.g. Mouse Physiology Core.)
The effects of blood flow in shaping the developing heart can be quantified with sophisticated flow visualization techniques from fluid mechanical engineering. (Image from J. Hove.)