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Pathobiology & Molecular Medicine

Photo of  Zhongyun Dong, MD, PhD

Zhongyun Dong, MD, PhD

  • Medical Degree: Anhui Medical University
  • Master's Degree: Peking Union Medical College
  • Doctoral Degree: Peking Union Medical College
  • Fellowship: The University of Texas MD Anderson Cancer Center
Contact Information
  • Vontz Center for Molecular Studies
  • 3125 Eden Avenue, Room 1308
  • ML 0508
  • Cincinnati, Ohio 45267-0508
  • Office 513-558-2176
  • Fax 513-558-6703
  • Email

Peer Reviewed Publications

Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan 2014. Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells. International journal of oncology, 45 3, 978-84

Chou, Da-Tren; Hong, Daeho; Saha, Partha; Ferrero, Jordan; Lee, Boeun; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N 2013. In vitro and in vivo corrosion, cytocompatibility and mechanical properties of biodegradable Mg-Y-Ca-Zr alloys as implant materials. Acta biomaterialia, 9 10, 8518-33

Hong, Daeho; Saha, Partha; Chou, Da-Tren; Lee, Boeun; Collins, Boyce E; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N 2013. In vitro degradation and cytotoxicity response of Mg-4% Zn-0.5% Zr (ZK40) alloy as a potential biodegradable material. Acta biomaterialia, 9 10, 8534-47

Cui, L., Chen, P., Tan, Z., and Dong, Z. 2012. Hemostatic gelatin sponge is a superior matrix to Matrigel for estabishment of LNCaP human prostate cancer in nude mice Prostate, DOI:10 1002/, pros. 22520

Cui, L., Dillehay, K. L., Chen, W., Shen, D., Dong, Z., W. Li 2012. Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis Mol Biol Reports, 39 , 7465-71

Cui, Lingling; Chen, Pingping; Tan, Zongqing; Li, Wenjie; Dong, Zhongyun 2012. Hemostatic gelatin sponge is a superior matrix to matrigel for establishment of LNCaP human prostate cancer in nude mice. The Prostate, 72 15, 1669-77

Oleksowicz, L., Jiu, Y., Bracken, R.B, Gaitonde, K., Burke, B., Succop, P., Levin, L., Dong, Z., and Lu,S. 2012. Secretory Phospholipase A2-lla is a Target Gene of the HER/HER2-Elicited Pathway and Potential Plasma Biomarket for Poor Prognosis of Prostate Cancer Prostate, 72 , 1140-49

Oleksowicz, Leslie; Liu, Yin; Bracken, R Bruce; Gaitonde, Krishnanath; Burke, Barbara; Succop, Paul; Levin, Linda; Dong, Zhongyun; Lu, Shan 2012. Secretory phospholipase A2-IIa is a target gene of the HER/HER2-elicited pathway and a potential plasma biomarker for poor prognosis of prostate cancer. The Prostate, 72 10, 1140-9

Tan, Z., Chen, P., Schneider, N., Glover, S., Cui, L., Torgue, J., Rixe, O., Spitz, H. B., an Dong, Z. 2012. Significant systemic therapeutic effects of high-LET immunoradiation by Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice Int J. Oncol, 40 , 1881-1888

Tan, Z., Wortman, M., Dillehay, K.L., Seibel, W., Evelyn, C. R., Smith, S. J., Malkas, L., Zheng, Y., Lu, S., and Dong, Z. 2012. Small molecule targeting of PCNA chromatin association inhibits tumor cell growth Mol Pharmacol, 81 , 811-9

Tan, Zongqing; Chen, Pingping; Schneider, Nathan; Glover, Samuel; Cui, Lingling; Torgue, Julien; Rixe, Olivier; Spitz, Henry B; Dong, Zhongyun 2012. Significant systemic therapeutic effects of high-LET immunoradiation by 212Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice. International journal of oncology, 40 6, 1881-8

Tan, Zongqing; Wortman, Matthew; Dillehay, Kelsey L; Seibel, William L; Evelyn, Chris R; Smith, Shanna J; Malkas, Linda H; Zheng, Yi; Lu, Shan; Dong, Zhongyun 2012. Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth. Molecular pharmacology, 81 6, 811-9

Xue, D., Yun Y., Tan Z., Dong Z., and M. J. Schultz 2012. In Vivo and In Vitro degradation behavior of magnesium alloys as biomaterials J. Mat. Sci. Tech., ,

Yun, Y., Pixley, S., X. Cui, T., Dong, Z., Collins, B., Shanov, V., Ko, S., Pai1, D., Yarmolenko, S., Schulz, M. J., and J. Sankar 2012. Carbon Nanomaterials: From Therapeutics to Regenerative Medicine Nanomedicine and Biotherapeutic Discovery, 2 , 1000104

Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer. Oncology reports, 25 6, 1511-6

Kupert, E., Anderson, M. Liu, Y., Succop, P., Levin, L., Wang, J., Wikenheisser-Brokamp, K., Chen, P., Ponney, S., Macdonald, T., Dong, Z., Starnes, S. and Lu, S. 2011. Plasma secretory phospholipase A2-lla as a potential biomarker for lung cancer in patients with solitary pulmonary nodules BMC Cancer, 11 , 513

Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan 2011. Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules. BMC cancer, 11 , 513

Cho, Hoon-Sung; Dong, Zhongyun; Pauletti, Giovanni M; Zhang, Jiaming; Xu, Hong; Gu, Hongchen; Wang, Lumin; Ewing, Rodney C; Huth, Christopher; Wang, Feng; Shi, Donglu 2010. Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: a multifunctional nanocarrier system for cancer diagnosis and treatment. ACS nano, 4 9, 5398-404

Dong, Zhongyun; Liu, Yin; Scott, Kieran F; Levin, Linda; Gaitonde, Krishnanath; Bracken, R Bruce; Burke, Barbara; Zhai, Qihui Jim; Wang, Jiang; Oleksowicz, Leslie; Lu, Shan 2010. Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer. Carcinogenesis, 31 11, 1948-55

Liu, Yin; Wu, Xiaoyang; Dong, Zhongyun; Lu, Shan 2010. The molecular mechanism of Vav3 oncogene on upregulation of androgen receptor activity in prostate cancer cells. International journal of oncology, 36 3, 623-33

Lu, Shan; Tan, Zongqin; Wortman, Matt; Lu, Shan; Dong, Zhongyun 2010. Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells. International journal of oncology, 36 2, 459-67

Lu, Shan; Tan, Zongqin; Wortman, Matthew; Lu, Shan; Dong, Zhongyun 2010. Preferential induction of G1 arrest in androgen-responsive human prostate cancer cells by androgen receptor signaling antagonists DL3 and antiandrogen bicalutamide. Cancer letters, 298 2, 250-7

Meng, Qinghang; Peng, Zhimin; Chen, Liang; Si, Jutong; Dong, Zhongyun; Xia, Ying 2010. Nuclear Factor-?B modulates cellular glutathione and prevents oxidative stress in cancer cells. Cancer letters, 299 1, 45-53

Yun, YeoHeung; Dong, Zhongyun; Tan, Zongqing; Schulz, Mark J 2010. Development of an electrode cell impedance method to measure osteoblast cell activity in magnesium-conditioned media. Analytical and bioanalytical chemistry, 396 8, 3009-15

Yun, Yeo-Heung; Eteshola, Edward; Bhattacharya, Amit; Dong, Zhongyun; Shim, Joon-Sub; Conforti, Laura; Kim, Dogyoon; Schulz, Mark J; Ahn, Chong H; Watts, Nelson 2009. Tiny medicine: nanomaterial-based biosensors. Sensors (Basel, Switzerland), 9 11, 9275-99

Guo, Yan; Shi, Donglu; Lian, Jie; Dong, Zhongyun; Wang, Wei; Cho, Hoonsung; Liu, Guokui; Wang, Lumin; Ewing, Rodney C 2008. Quantum dot conjugated hydroxylapatite nanoparticles for in vivo imaging. Nanotechnology, 19 17, 175102

Lee, Kiwon; Liu, Yin; Mo, Jun Qin; Zhang, Jinsong; Dong, Zhongyun; Lu, Shan 2008. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. BMC cancer, 8 , 158

Liu, Yin; Mo, Jun Qin; Hu, Qiande; Boivin, Gregory; Levin, Linda; Lu, Shan; Yang, Dianer; Dong, Zhongyun; Lu, Shan 2008. Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer. Cancer research, 68 15, 6396-406

Lu, Shan; Lee, Juwon; Revelo, Monica; Wang, Xiaohong; Lu, Shan; Dong, Zhongyun 2007. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 13 19, 5692-702

Lu, Shan; Wang, Amy; Lu, Shan; Dong, Zhongyun 2007. A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells. Molecular cancer therapeutics, 6 7, 2057-64

Wang, Daren; Lu, Shan; Dong, Zhongyun 2007. Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide. The Prostate, 67 16, 1825-33

Yun, YeoHeung; Bange, Adam; Shanov, Vesselin N; Heineman, William R; Halsall, H Brian; Dong, Zhongyun; Jazieh, Abdul; Tu, Yi; Wong, Danny; Pixley, Sarah; Behbehani, Michael; Schulz, Mark J 2007. A carbon nanotube needle biosensor. Journal of nanoscience and nanotechnology, 7 7, 2293-300

Yun, Yeoheung; Dong, Zhongyun; Shanov, Vesselin N; Schulz, Mark J 2007. Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrodes in a microfluidic channel. Nanotechnology, 18 46, 465505

Yun, Yeoheung; Gollapudi, Ram; Shanov, Vesselin; Schulz, Mark J; Dong, Zhongyun; Jazieh, Abdul; Heineman, William R; Halsall, H Brian; Wong, Danny K Y; Bange, Adam; Tu, Yi; Subramaniam, Srinivas 2007. Carbon nanotubes grown on stainless steel to form plate and probe electrodes for chemical/biological sensing. Journal of nanoscience and nanotechnology, 7 3, 891-7

Dong, Zhongyun; Liu, Yin; Lu, Shan; Wang, Amy; Lee, Kiwon; Wang, Lu-Hai; Revelo, Monica; Lu, Shan 2006. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer. Molecular endocrinology (Baltimore, Md.), 20 10, 2315-25

Lee, Juwon; Wang, Amy; Hu, Qiande; Lu, Shan; Dong, Zhongyun 2006. Adenovirus-mediated interferon-beta gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice. International journal of oncology, 29 6, 1405-12

Lu, Shan; Dong, Zhongyun 2006. Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. The Prostate, 66 9, 996-1004

Zhang, Fahao; Lee, Juwon; Wang, Daren; Dong, Zhongyun 2006. Differential growth of IFN-beta-engineered tumor cells in nude and IFN receptor-null mice. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 26 2, 108-18

Liu, Guozhen; Zhang, Fahao; Lee, Juwon; Dong, Zhongyun 2005. Selective induction of interleukin-8 expression in metastatic melanoma cells by transforming growth factor-beta 1. Cytokine, 31 3, 241-9

Uehara, Hisanori; Troncoso, Patricia; Johnston, Dennis; Bucana, Corazon D; Dinney, Colin; Dong, Zhongyun; Fidler, Isaiah J; Pettaway, Curtis A 2005. Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage. The Prostate, 64 1, 40-9

Zhang, Fahao; Lee, Juwon; Lu, Shan; Pettaway, Curtis A; Dong, Zhongyun 2005. Blockade of transforming growth factor-beta signaling suppresses progression of androgen-independent human prostate cancer in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 11 12, 4512-20

Lu, Weixin; Su, Jindong; Kim, Lee Su; Bucana, Corazon D; Donawho, Cherrie; He, Junqing; Fidler, Isaiah J; Dong, Zhongyun 2003. Active specific immunotherapy against occult brain metastasis. Cancer research, 63 6, 1345-50

Ozawa, Shutaro; Lu, Weixin; Bucana, Corazon D; Kanayama, Hiro-Omi; Shinohara, Hisashi; Fidler, Isaiah J; Dong, Zhongyun 2003. Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International journal of oncology, 22 5, 977-84

Davies, Michael A; Kim, Sun J; Parikh, Nila U; Dong, Zhongyun; Bucana, Corazon D; Gallick, Gary E 2002. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 6, 1904-14

Harmey, Judith H; Bucana, Corazon D; Lu, Weixin; Byrne, Anne Marie; McDonnell, Susan; Lynch, Conor; Bouchier-Hayes, David; Dong, Zhongyun 2002. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. International journal of cancer. Journal international du cancer, 101 5, 415-22

Izawa, Jonathan I; Sweeney, Paul; Perrotte, Paul; Kedar, Daniel; Dong, Zhongyun; Slaton, Joel W; Karashima, Takashi; Inoue, Keji; Benedict, William F; Dinney, Colin P N 2002. Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 4, 1258-70

Lu, Weixin; Dong, Zhongyun; Donawho, Cherrie; Fidler, Isaiah J 2002. Specific immunotherapy against occult cancer metastases. International journal of cancer. Journal international du cancer, 100 4, 480-5

Makar, Tapas Kumar; Wilt, Susan; Dong, Zhongyun; Fishman, Paul; Mouradian, M Maral; Dhib-Jalbut, Suhayl 2002. IFN-beta gene transfer into the central nervous system using bone marrow cells as a delivery system. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22 7, 783-91

Takeuchi, Osamu; Sato, Shintaro; Horiuchi, Takao; Hoshino, Katsuaki; Takeda, Kiyoshi; Dong, Zhongyun; Modlin, Robert L; Akira, Shizuo 2002. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. Journal of immunology (Baltimore, Md. : 1950), 169 1, 10-4

Zhang, Fahao; Lu, Weixin; Dong, Zhongyun 2002. Tumor-infiltrating macrophages are involved in suppressing growth and metastasis of human prostate cancer cells by INF-beta gene therapy in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 9, 2942-51

Shi D.;Cho H.;Huth C.;Wang F.;Dong Z.;Pauletti G.;Lian J.;Wang W.;Liu G.;Bud'Ko S.;Wang L.;Ewing R. 12-18-2009. Conjugation of quantum dots and Fe<inf>3</inf> O<inf>4</inf> on carbon nanot Applied Physics Letters, 95 22,

Yun Y.H.;Shanov V.;Schulz M.J.;Dong Z.;Jazieh A.;Heineman W.R.;Halsall H.B.;Wong D.K.Y.;Bange A.;Tu Y.;Subramaniam S. 12-14-2006. High sensitivity carbon nanotube tower electrodes Sensors and Actuators, B: Chemical, 120 1, 298-304

Koo Y.;Lee H.;Dong Z.;Kotoka R.;Sankar J.;Huang N.;Yun Y. 12-01-2017. The Effects of Static and Dynamic Loading on Biodegradable Magnesium Pins in Vitro and in Vivo Scientific Reports, 7 1,

Dillehay K.;Lu S.;Dong Z. 12-01-2014. Antitumor effects of a novel small molecule targeting PCNA chromatin association in prostate cancer Molecular Cancer Therapeutics, 13 12, 2817-2826

Jang Y.;Tan Z.;Jurey C.;Collins B.;Badve A.;Dong Z.;Park C.;Kim C.S.;Sankar J.;Yun Y. 12-01-2014. Systematic understanding of corrosion behavior of plasma electrolytic oxidation treated AZ31 magnesi Materials Science and Engineering C, 45 , 45-55

Yun Y.H.;Shanov V.N.;Bange A.;Heineman W.R.;Halsall H.B.;Seth G.;Pixley S.K.;Behbehani M.;Bhattacharya A.;Dong Z.;Yarmolenko S.;Kang I.;Schulz M.J. 12-01-2009. Carbon nanotube smart materials for biology and medicine NanoScience in Biomedicine, , 451-484

Yun Y.H.;Dong Z.;Shanov V.;Heineman W.R.;Halsall H.B.;Bhattacharya A.;Conforti L.;Narayan R.K.;Ball W.S.;Schulz M.J. 12-01-2007. Nanotube electrodes and biosensors Nano Today, 2 6, 30-37

Yun Y.H.;Bange A.;Shanov V.N.;Heineman W.R.;Brian Halsall H.;Dong Z.;Jazieh A.;Tu Y.;Wong D.;Pixley S.;Behbehani M.;Schulz M.J. 12-01-2006. Fabrication and characterization of a multiwall carbon nanotube needle biosensor 2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006, 1 , 280-283

Xie K.;Bielenberg D.;Huang S.;Xu L.;Salas T.;Juang S.;Dong Z.;Fidler I. 12-01-1997. Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the Clinical Cancer Research, 3 12 I, 2283-2294

Kumar R.;Dong Z.;Fidler I. 12-01-1996. Differential Regulation of Metalloelastase Activity in Murine Peritoneal Macrophages by Granulocyte- Journal of Immunology, 157 11, 5104-5111

Shi D.;Guo Y.;Wang W.;Cho H.;Lian J.;Wang L.;Ewing R.G.;Liu G.;Dong Z. 11-28-2006. Deposition of rare-earth doped nanophosphors on multi-wall carbon nanotube surfaces - a new approach Proceedings of the International Conference on Manufacturing Science and Engineering, 2006 ,

Xie K.;Huang S.;Wang Y.;Beltran P.;Juang S.;Dong Z.;Reed J.;McDonnell T.;McConkey D.;Fidler I. 11-27-1996. Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis Cancer Immunology Immunotherapy, 43 2, 109-115

Yun Y.;Dong Z.;Shanov V.;Schulz M. 11-21-2007. Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrode Nanotechnology, 18 46,

Shi D.;Guo Y.;Dong Z.;Lian J.;Wang W.;Liu G.;Wang L.;Ewing R. 11-19-2007. Quantum-dot-activated luminescent carbon nanotubes via a nano scale surface functionalization for in Advanced Materials, 19 22, 4033-4037

Zhao D.;Wang T.;Hoagland W.;Benson D.;Dong Z.;Chen S.;Chou D.;Hong D.;Wu J.;Kumta P.;Heineman W. 11-01-2016. Visual H<inf>2</inf> sensor for monitoring biodegradation of magnesium implants in vivo Acta Biomaterialia, 45 , 399-409

Yun Y.;Eteshola E.;Bhattacharya A.;Dong Z.;Shim J.;Conforti L.;Kim D.;Schulz M.;Ahn C.;Watts N. 11-01-2009. Tiny medicine: Nanomaterial-based biosensors Sensors, 9 11, 9275-9299

Yun Y.;Dong Z.;Shanov V.;Bange A.;Heineman W.;Halsall H.;Conforti L.;Bhattacharya A.;Schulz M. 11-01-2007. On-line carbon nanotube-based biosensors in microfluidic channels Proceedings of SPIE - The International Society for Optical Engineering, 6528 ,

Killion J.;Radinsky R.;Dong Z.;Fishbeck R.;Whitworth P.;Fidler I. 11-01-1993. The immunogenic properties of drug-resistant murine tumor cells do not correlate with expression of Cancer Immunology Immunotherapy, 36 6, 381-386

Lu W.;Fidler I.;Dong Z. 10-15-1999. Eradication of primary murine fibrosarcomas and induction of systemic immunity by adenovirus mediate Cancer Research, 59 20, 5202-5208

Yun Y.;Dong Z.;Yang D.;Shanov V.;Yarmolenko S.;Xu Z.;Kumta P.;Sfeir C.;Doepke A.;Schulz M. 09-17-2009. Biodegradable Mg for bone implants: Corrosion and osteoblast culture studies ASME International Mechanical Engineering Congress and Exposition, Proceedings, 15 , 125-129

Guo Y.;Shi D.;Cho H.;Dong Z.;Kulkarni A.;Pauletti G.;Wang W.;Lian J.;Liu W.;Ren L.;Zhang Q.;Liu G.;Huth C.;Wang L.;Ewing R. 09-10-2008. In vivo imaging and drug storage by quantum-dot-conjugated carbon nanotubes Advanced Functional Materials, 18 17, 2489-2497

Joshi M.;Salunke P.;Zhang G.;Chaswal V.;Dong Z.;Shanov V. 09-04-2015. Magnesium Single Crystal as a Biodegradable Implant Material Biomaterials Science: Processing, Properties and Applications V: Ceramic Transactions, Volume 254, , 97-113

Guo Y.;Wang W.;Cho H.S.;Lian J.;Ewing R.;Wang L.;Liu G.K.;Dong Z.Y.;Shi D. 08-23-2007. Luminescent carbon nanotubes for biomedical diagnosis and treatment 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings, 2 , 251-254

Dong Z.;Yoneda J.;Kumar R.;Fidler I.J. 08-17-1998. Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce gra Journal of Experimental Medicine, 188 4, 755-763

Yun Y.;Dong Z.;Yang D.;Schulz M.;Shanov V.;Yarmolenko S.;Xu Z.;Kumta P.;Sfeir C. 08-01-2009. Biodegradable Mg corrosion and osteoblast cell culture studies Materials Science and Engineering C, 29 6, 1814-1821

Lu W.;Dong Z.;Donawho C.;Fidler I. 08-01-2002. ICAM-1 expression and the soluble ICAM-1 level for evaluating the metastatic potential of gastric ca International Journal of Cancer, 100 4, 486-490

Yun Y.;Dong Z.;Shanov V.;Doepke A.;Heineman W.;Halsall H.;Bhattacharya A.;Wong D.;Schulz M. 07-28-2008. Fabrication and characterization of carbon nanotube array electrodes with gold nanoparticle tips Sensors and Actuators, B: Chemical, 133 1, 208-212

Yun Y.;Bange A.;Shanov V.;Heineman W.;Brian Halsall H.;Pixley S.;Behbehani M.;Dong Z.;Tu Y.;Yarmolenko S.;Neralla S.;Schulz M. 07-20-2006. Carbon nanotube array smart materials Proceedings of SPIE - The International Society for Optical Engineering, 6172 ,

Olson M.;Lee J.;Zhang F.;Wang A.;Dong Z. 07-17-2006. Inducible nitric oxide synthase activity is essential for inhibition of prostatic tumor growth by in Cancer Gene Therapy, 13 7, 676-685

Xie K.;Huang S.;Dong Z.;Gutman M.;Fidler I. 07-15-1995. Direct Correlation between Expression of Endogenous Inducible Nitric Oxide Synthase and Regression o Cancer Research, 55 14, 3123-3131

Zhang F.;Zhao G.;Dong Z. 07-07-2001. Phosphatidylcholine-specific phospholipase C regulates activation of RAW264.7 macrophage-like cells Journal of Leukocyte Biology, 69 6, 1060-1066

Cui L.;Dillehay K.;Chen W.;Shen D.;Dong Z.;Li W. 07-01-2012. Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: A meta-analysis Molecular Biology Reports, 39 7, 7465-7471

Xue D.;Tan Z.;Schulz M.;Vanooij W.;Sankar J.;Yun Y.;Dong Z. 07-01-2012. Corrosion studies of modified organosilane coated magnesium-yttrium alloy in different environments Materials Science and Engineering C, 32 5, 1230-1236

Zhang F.;Zhao G.;Dong Z. 06-21-2001. Phosphatidylcholine-specific phospholipase C and D in stimulation of RAW264.7 mouse macrophage-like International Immunopharmacology, 1 7, 1375-1384

Dong Z.;Radinsky R.;Fan D.;Tsan R.;Bucana C.D.;Wilmanns C.;Fidler I.J. 06-15-1994. Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon ca Journal of the National Cancer Institute, 86 12, 913-920

Shi D.;Cho H.S.;Chen Y.;Xu H.;Gu H.;Lian J.;Wang W.;Liu G.;Huth C.;Wang L.;Ewing R.C.;Budko S.;Pauletti G.M.;Dong Z. 06-05-2009. Fluorescent polystyrene-Fe<inf>3</inf>O<inf>4</inf> composite nanospheres fo Advanced Materials, 21 21, 2170-2173

Yun Y.;Schulz M.;Bange A.;Heineman W.;Halsall H.;Shanov V.;Behbehani M.;Pixley S.;Bhattacharya A.;Dong Z.;Wong D. 06-01-2006. A nanotube composite microelectrode for monitoring dopamine levels using cyclic voltammetry and diff Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems, 220 2, 53-60

Fidler I.J.;Wilmanns C.;Staroselsky A.;Radinsky R.;Dong Z.;Fan D. 06-01-1994. Modulation of tumor cell response to chemotherapy by the organ environment Cancer and Metastasis Reviews, 13 2, 209-222

Zhao D.;Wang T.;Kuhlmann J.;Dong Z.;Chen S.;Joshi M.;Salunke P.;Shanov V.;Hong D.;Kumta P.;Heineman W. 05-01-2016. In vivo monitoring the biodegradation of magnesium alloys with an electrochemical H<inf>2</ Acta Biomaterialia, 36 , 361-368

Fidler I.J.;Singh R.K.;Yoneda J.;Kumar R.;Xu L.;Dong Z.;Bielenberg D.R.;McCarty M.;Ellis L.M. 05-01-2000. Critical determinants of neoplastic angiogenesis Cancer Journal, 6 SUPPL. 3,

Yun Y.H.;Dong Z.;Tan Z.;Schulz M.J.;Shanov V. 04-30-2009. Fibroblast cell behavior on chemically functionalized carbon nanomaterials Materials Science and Engineering C, 29 3, 719-725

Guo Y.;Shi D.;Lian J.;Dong Z.;Wang W.;Cho H.;Liu G.;Wang L.;Ewing R. 04-30-2008. Quantum dot conjugated hydroxylapatite nanoparticles for in vivo imaging Nanotechnology, 19 17,

Shi D.;Guo Y.;Dong Z.;Lian J.;Wang W.;Liu G.;Wang L.;Ewing R. 04-21-2008. Quantum-dot-activated luminescent carbon nanotubes via a nano scale surface functionalization for in Advanced Materials, 20 8, 1

Yun Y.H.;Bange A.;Heineman W.R.;Halsall H.B.;Shanov V.N.;Dong Z.;Pixley S.;Behbehani M.;Jazieh A.;Tu Y.;Wong D.K.Y.;Bhattacharya A.;Schulz M.J. 04-10-2007. A nanotube array immunosensor for direct electrochemical detection of antigen-antibody binding Sensors and Actuators, B: Chemical, 123 1, 177-182

Zhao D.;Wang T.;Guo X.;Kuhlmann J.;Doepke A.;Dong Z.;Shanov V.;Heineman W. 04-01-2016. Monitoring Biodegradation of Magnesium Implants with Sensors JOM, 68 4, 1204-1208

Schneider N.;Lobaugh M.;Tan Z.;Sandwall P.;Chen P.;Glover S.;Cui L.;Murry M.;Dong Z.;Torgue J.;Spitz H. 04-01-2013. Biodistribution of <sup>212</sup>Pb conjugated trastuzumab in mice Journal of Radioanalytical and Nuclear Chemistry, 296 1, 75-81

Xie K.;Huang S.;Dong Z.;Juang S.;Gutman M.;Xie Q.;Nathan C.;Fidler I. 04-01-1995. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates m Journal of Experimental Medicine, 181 4, 1333-1343

Xie B.;Dong Z.;Fidler I. 04-01-1994. Regulatory mechanisms for the expression of type IV collagenases/gelatinases in murine macrophages Journal of Immunology, 152 7, 3637-3644

Dong Z.;Qi X.;Fidler I. 04-01-1993. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine Journal of Experimental Medicine, 177 4, 1071-1077

Dong Z.;Kumar R.;Yang X.;Fidler I. 03-21-1997. Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung ca Cell, 88 6, 801-810

Xie K.;Huang S.;Dong Z.;Juang S.;Wang Y.;Fidler I. 03-19-1997. Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase Journal of the National Cancer Institute, 89 6, 421-427

Wu J.;Zhao D.;Ohodnicki J.M.;Lee B.;Roy A.;Yao R.;Chen S.;Dong Z.;Heineman W.R.;Kumta P.N. 03-12-2018. In Vitro and in Vivo Evaluation of Multiphase Ultrahigh Ductility Mg-Li-Zn Alloys for Cardiovascular ACS Biomaterials Science and Engineering, 4 3, 919-932

Zhao D.;Wang T.;Nahan K.;Guo X.;Zhang Z.;Dong Z.;Chen S.;Chou D.;Hong D.;Kumta P.;Heineman W. 03-01-2017. In vivo characterization of magnesium alloy biodegradation using electrochemical H<inf>2</i Acta Biomaterialia, 50 , 556-565

Dillehay K.;Seibel W.;Zhao D.;Lu S.;Dong Z. 03-01-2015. Target validation and structure-activity analysis of a series of novel PCNA inhibitors Pharmacology Research and Perspectives, 3 2,

Jang Y.;Tan Z.;Jurey C.;Xu Z.;Dong Z.;Collins B.;Yun Y.;Sankar J. 03-01-2015. Understanding corrosion behavior of Mg-Zn-Ca alloys from subcutaneous mouse model: Effect of Zn elem Materials Science and Engineering C, 48 , 28-40

Xue D.;Yun Y.;Tan Z.;Dong Z.;Schulz M. 03-01-2012. In Vivo and In Vitro Degradation Behavior of Magnesium Alloys as Biomaterials Journal of Materials Science and Technology, 28 3, 261-267

O'Brian C.A.;Fan D.;Ward N.E.;Dong Z.;Iwamoto L.;Gupta K.P.;Earnest L.E.;Fidler I.J. 03-01-1991. Transient enhancement of multidrug resistance by the bile acid deoxycholate in murine fibrosarcoma c Biochemical Pharmacology, 41 5, 797-806

Dong Z.;Greene G.;Pettaway C.;Dinney C.;Eue I.;Lu W.;Bucana C.;Balbay M.;Bielenberg D.;Fidler I. 02-15-1999. Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineere Cancer Research, 59 4, 872-879

Smith S.J.;Gu L.;Phipps E.A.;Dobrolecki L.E.;Mabrey K.S.;Gulley P.;Dillehay K.L.;Dong Z.;Fields G.B.;Chen Y.R.;Ann D.;Hickey R.J.;Malkas L.H. 02-01-2015. A peptide mimicking a region in proliferating cell nuclear antigen specific to key protein interacti Molecular Pharmacology, 87 2, 263-276

Shi D.;Lian J.;Wang W.;Liu G.;He P.;Dong Z.;Wang L.;Ewing R. 01-19-2006. Luminescent carbon nanotubes by surface functionalization Advanced Materials, 18 2, 189-193

Zhao D.;Wu J.;Chou D.T.;Hoagland W.;Benson D.;Dong Z.;Kumta P.N.;Heineman W.R. 01-01-2020. Visual Hydrogen Mapping Sensor for Noninvasive Monitoring of Bioresorbable Magnesium Implants In Viv JOM, ,

Lu S.;Dong Z. 01-01-2019. Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhi PLoS ONE, 14 10,

Yin Z.;Dong Z.;Cahay M.;Pixley S.;Haworth K.J.;Rahimi M.;Goh S.K.;Starnes S.;Patwardhan M.;Chaudhary S.;Schulz M.J. 01-01-2019. Carbon nanotube wire for use in precision medical devices Nanotube Superfiber Materials: Science, Manufacturing, Commercialization, , 825-849

Joshi M.;Salunke P.;Zhang G.;Chaswal V.;Dong Z.;Shanov V. 01-01-2015. Magnesium single crystal as a biodegradable implant material Ceramic Transactions, 254 , 97-113

Yun Y.;Jang Y.;Wang J.;Dong Z.;Shanov V.;Sankar J.;Koo Y.;White L.;Collins B. 01-01-2014. Biodegradable magnesium implant: In vivo and in vitro convergence ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), 14 ,

Schulz M.;Doepke A.;Guo X.;Kuhlmann J.;Halsall B.;Heineman W.;Dong Z.;Tan Z.;Xue D.;Lee N.;Yun Y.;Liu Y.;Hurd D.;Shanov V.;Rai D.;Witte F.;Kumar D.;Yarmolenko S.;Pixley S.;Hopkins T.;Jayasinghe C.;Sundaramurthy S. 01-01-2010. Responsive biosensors for biodegradable magnesium implants ASME International Mechanical Engineering Congress and Exposition, Proceedings, 14 , 109-116

Yun Y.;Dong Z.;Lee N.;Liu Y.;Xue D.;Guo X.;Kuhlmann J.;Doepke A.;Halsall H.;Heineman W.;Sundaramurthy S.;Schulz M.;Yin Z.;Shanov V.;Hurd D.;Nagy P.;Li W.;Fox C. 01-01-2009. Revolutionizing biodegradable metals Materials Today, 12 10, 22-32

Cao G.;Su J.;Lu W.;Zhang F.;Zhao G.;Marteralli D.;Dong Z. 01-01-2002. Multiple arteriovenous malformations with hemorrhage Acta Neurochirurgica, 144 1, 97-101

Cao G.;Su J.;Lu W.;Zhang F.;Zhao G.;Marteralli D.;Dong Z. 01-01-2001. Adenovirus-mediated interferon-? gene therapy suppresses growth and metastasis of human prostate can Cancer Gene Therapy, 8 7, 497-505

Bruns C.;Shinohara H.;Harbison M.;Davis D.;Nelkin G.;Killion J.;McConkey D.;Dong Z.;Fidler I. 01-01-2000. Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 i Cancer Research, 60 1, 2-7

Kumar R.;Xie K.;Eue I.;Dong Z.;Killion J.;Fidler I. 01-01-2000. Differential regulation of type IV collagenases and metalloelastase in murine macrophages by the syn International Journal of Immunopharmacology, 22 6, 431-443

Kumar R.;Yoneda J.;Fidler I.J.;Dong Z. 01-01-1999. GM-CSF-transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages an Journal of Leukocyte Biology, 65 1, 102-108

Dong Z.;Juang S.;Kumar R.;Eue I.;Xie K.;Bielenberg D.;Lu W.;Bucana C.;Yang X.;Fidler I. 01-01-1998. Suppression of tumorigenicity and metastasis in murine UV-2237 fibrosarcoma cells by infection with Cancer Immunology Immunotherapy, 46 3, 137-146

Dong Z.;Killion J.;Kumar R.;Eue I.;Yang X.;Lu W.;Su B.;Fidler I. 01-01-1998. Activation of cytokine production, tumoricidal properties, and tyrosine phosphorylation of MAPKs in Journal of Leukocyte Biology, 63 6, 766-774

Eue I.;Kumar R.;Dong Z.;Killion J.;Fidler I. 01-01-1998. Induction of nitric oxide production and tumoricidal properties in murine macrophages by a new synth Journal of Immunotherapy, 21 5, 340-351

Dinney C.;Parker C.;Dong Z.;Fan D.;Eve B.;Bucana C.;Radinsky R. 01-01-1997. Therapy of human transitioneal cell carcinoma of the bladder by oral administration of the epidermal Clinical Cancer Research, 3 2, 161-168

Dong Z.;Yang X.;Fidler I. 01-01-1997. Neutralization of endogenous interferon-? increases the efficiency of adenoviral vector-mediated gen Journal of Interferon and Cytokine Research, 17 7, 401-407

Kumar R.;Eue I.;Dong Z.;Killion J.;Fidler I. 01-01-1997. Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptid Cancer Biotherapy and Radiopharmaceuticals, 12 5, 333-340

Wei Q.;Cheng L.;Xie K.;Bucana C.;Dong Z. 01-01-1997. Direct correlation between DNA repair capacity and metastatic potential of K-1735 murine melanoma ce Journal of Investigative Dermatology, 108 1, 3-6

Killion J.;Bucana C.;Radinsky R.;Dong Z.;O'Reilly T.;Bilbe G.;Tarcsay L.;Fidler I. 01-01-1996. Maintenance of intestinal epithelium structural integrity and mucosal leukocytes during chemotherapy Cancer Biotherapy and Radiopharmaceuticals, 11 6, 363-371

Xie K.;Dong Z.;Fidler I. 01-01-1996. Activation of nitric oxide synthase gene for inhibition of cancer metastasis Journal of Leukocyte Biology, 59 6, 797-803

Dong Z.;Yang X.;Xie K.;Juang S.;Llansa N.;Fidler I. 01-01-1995. Activation of inducible nitric oxide synthase gene in murine macrophages requires protein phosphatas Journal of Leukocyte Biology, 58 6, 725-732

Radinsky R.;Risin S.;Fan D.;Dong Z.;Bielenberg D.;Bucana C.;Fidler I. 01-01-1995. Level and Function of Epidermal Growth Factor Receptor Predict the Metastatic Potential of Human Col Clinical Cancer Research, 1 1, 19-31

Dong Z.;Staroselsky A.;Qi X.;Xie K.;Fidler I. 01-01-1994. Inverse Correlation between Expression of Inducible Nitric Oxide Synthase Activity and Production of Cancer Research, 54 3, 789-793

Fan D.;Poste G.;Ruffolo R.;Dong Z.;Seid C.;Earnest L.;Campbell T.;Clyne R.;Beltran P.;Fidler I. 01-01-1994. Circumvention of multidrug resistance in murine fibrosarcoma and colon carcinoma cells by treatment International Journal of Oncology, 4 4, 789-798

Bucana C.;Radinsky R.;Dong Z.;Sanchez R.;Brigati D.;Fidler I. 01-01-1993. A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide pr Journal of Histochemistry and Cytochemistry, 41 4, 499-506

Dong Z.;O'Brian C.;Fidler I. 01-01-1993. Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein-tyrosine Journal of Leukocyte Biology, 53 1, 53-60

Dong Z.;Qi X.;Xie K.;Fidler I. 01-01-1993. Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolys Journal of Immunology, 151 5, 2717-2724

Xie K.;Huang S.;Dong Z.;Fidler I.J. 01-01-1993. Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric International Journal of Oncology, 3 6, 1043-1048

Dong Z.;Ward N.E.;Fan D.;Gupta K.P.;O'Brian C.A. 01-01-1991. In vitro model for intrinsic drug resistance: Effects of protein kinase C activators on the chemosen Molecular Pharmacology, 39 4, 563-569

Dong Z.;Lu S.;Zhang Y. 01-01-1989. Effects of Pretreatment with Protein Kinase C Activators on Macrophage Activation for Tumor Cytotoxi Immunobiology, 179 4-5, 382-394

Dong Z.Y.;Zhang Y.H. 01-01-1987. Inhibitory effect of a mycotoxin, Fusarin C, on macrophage activation and macrophage mediated cytoto Journal of Experimental and Clinical Cancer Research, 6 1, 31-38