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Department of Internal Medicine

Immunology, Allergy and Rheumatology

Photo of  Manuel Vilareal, MD

Manuel Vilareal, MD

Clinical Interest

Allergy and Immunology
Geriatric Medicine

Specialties

Allergy and Immunology
Geriatric Medicine
Internal Medicine

Education/Credentials
  • Bachelor's Degree: University of the Philippines
  • Medical Degree: De La Salle University-Emilio Aguinaldo College of Medicine
Board Certifications & Licenses
  • American Board of Allergy and Immunology 12/31/2015
Contact Information
  • Health Professions Building
  • 3255 Eden Avenue
  • Suite 350
  • Cincinnati, Ohio 45267-0563
  • Office 513-558-4701
  • Fax 513-558-3799
  • Email manuel.vilareal@uc.edu

Peer Reviewed Publications

Kannan, Jennifer A; Brokamp, Cole; Bernstein, David I; LeMasters, Grace K; Hershey, Gurjit K Khurana; Villareal, Manuel S; Lockey, James E; Ryan, Patrick H 2017. Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort. Pediatric allergy, immunology, and pulmonology, 30 1, 31-38

Kannan, Jennifer A; Bernstein, David I; Bernstein, Cheryl K; Ryan, Patrick H; Bernstein, Jonathan A; Villareal, Manuel S; Smith, Andrew M; Lenz, Peter H; Epstein, Tolly G 2015. Significant predictors of poor quality of life in older asthmatics. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 115 3, 198-204

Epstein, Tolly G; Kesavalu, Banurekha; Bernstein, Cheryl K; Ryan, Patrick H; Bernstein, Jonathan A; Zimmermann, Nives; Lummus, Zana; Villareal, Manuel S; Smith, Andrew M; Lenz, Peter H; Bernstein, David I 2013. Chronic traffic pollution exposure is associated with eosinophilic, but not neutrophilic inflammation in older adult asthmatics. The Journal of asthma : official journal of the Association for the Care of Asthma, 50 9, 983-9

Epstein, Tolly G; LeMasters, Grace K; Bernstein, David I; Ericksen, Mark B; Martin, Lisa J; Ryan, Patrick H; Biagini Myers, Jocelyn M; Butsch Kovacic, Melinda S; Lindsey, Mark A; He, Hua; Reponen, Tiina; Villareal, Manuel S; Lockey, James E; Bernstein, Cheryl K; Khurana Hershey, Gurjit K 2012. Genetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 108 3, 145-50

Epstein, Tolly G; Ryan, Patrick H; LeMasters, Grace K; Bernstein, Cheryl K; Levin, Linda S; Bernstein, Jonathan A; Villareal, Manuel S; Bernstein, David I 2012. Poor asthma control and exposure to traffic pollutants and obesity in older adults. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 108 6, 423-428.e2

Biagini Myers, Jocelyn M; Wang, Ning; LeMasters, Grace K; Bernstein, David I; Epstein, Tolly G; Lindsey, Mark A; Ericksen, Mark B; Chakraborty, Ranajit; Ryan, Patrick H; Villareal, Manuel S; Burkle, Jeff W; Lockey, James E; Reponen, Tiina; Khurana Hershey, Gurjit K 2010. Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort. The Journal of investigative dermatology, 130 2, 430-7

Villareal, M S; Klaustermeyer, W B; Hahn, T J; Gordon, E H 1996. Osteoporosis in steroid-dependent asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 76 4, 369-72

Reponen T.;Singh U.;Vesper S.;Johansson E.;Adhikari A.;Ryan P.;Levin L.;Zheng S.;Burkle J.;Grinshpun S.A.;Bernstein D.I.;Lockey J.;Villareal M.;Hershey G.K.K.;LeMasters G. 12-01-2011. Effect of microbial exposure on the development of Asthma in children 12th International Conference on Indoor Air Quality and Climate 2011, 1 , 552-553

Ryan P.;Bernstein D.;Lockey J.;Reponen T.;Levin L.;Grinshpun S.;Villareal M.;Khurana Hershey G.;Burkle J.;LeMasters G. 12-01-2009. Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at ag American Journal of Respiratory and Critical Care Medicine, 180 11, 1068-1075

Campo P.;Kalra H.;Levin L.;Reponen T.;Olds R.;Lummus Z.;Cho S.;Khurana Hershey G.;Lockey J.;Villareal M.;Stanforth S.;LeMasters G.;Bernstein D. 12-01-2006. Influence of dog ownership and high endotoxin on wheezing and atopy during infancy Journal of Allergy and Clinical Immunology, 118 6, 1271-1278

LeMasters G.;Wilson K.;Levin L.;Biagini J.;Ryan P.;Lockey J.;Stanforth S.;Maier S.;Yang J.;Burkle J.;Villareal M.;Khurana Hershey G.;Bernstein D. 10-01-2006. High prevalence of aeroallergen sensitization among infants of atopic parents Journal of Pediatrics, 149 4, 505-511

Johansson E.;Reponen T.;Vesper S.;Levin L.;Lockey J.;Ryan P.;Bernstein D.;Villareal M.;Khurana Hershey G.;Schaffer C.;LeMasters G. 09-01-2013. Microbial content of household dust associated with exhaled NO in asthmatic children Environment International, 59 , 141-147

Brunst K.;Ryan P.;Lockey J.;Bernstein D.;Mckay R.;Khurana Hershey G.;Villareal M.;Biagini Myers J.;Levin L.;Burkle J.;Evans S.;Lemasters G. 08-01-2012. Unraveling the relationship between aeroallergen sensitization, gender, second-hand smoke exposure, Pediatric Allergy and Immunology, 23 5, 479-487

Reponen T.;Vesper S.;Levin L.;Johansson E.;Ryan P.;Burkle J.;Grinshpun S.;Zheng S.;Bernstein D.;Lockey J.;Villareal M.;Khurana Hershey G.;Lemasters G. 08-01-2011. High environmental relative moldiness index during infancy as a predictor of asthma at 7 years of ag Annals of Allergy, Asthma and Immunology, 107 2, 120-126

Ryan P.;LeMasters G.;Biagini J.;Bernstein D.;Grinshpun S.;Shukla R.;Wilson K.;Villareal M.;Burkle J.;Lockey J. 08-01-2005. Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic Journal of Allergy and Clinical Immunology, 116 2, 279-284

Newman N.;Ryan P.;Le Masters G.;Levin L.;Bernstein D.;Hershey G.;Lockey J.;Villareal M.;Reponen T.;Grinshpun S.;Sucharew H.;Dietrich K. 06-01-2013. Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of Environmental Health Perspectives, 121 6, 731-736

Biagini Myers J.;Khurana Hershey G.;Deka R.;Burkle J.;Levin L.;Bernstein D.;Villareal M.;Lockey J.;Reponen T.;Gareri J.;Lubetsky A.;Koren G.;Lemasters G. 06-01-2012. Asking the right questions to ascertain early childhood secondhand smoke exposures Journal of Pediatrics, 160 6, 1050-1051

Biagini J.;LeMasters G.;Ryan P.;Levin L.;Reponen T.;Bernstein D.;Villareal M.;Khurana Hershey G.;Burkle J.;Lockey J. 06-01-2006. Environmental risk factors of rhinitis in early infancy Pediatric Allergy and Immunology, 17 4, 278-284

Smith A.M.;Villareal M.;Bernstein D.I.;Swikert D.J. 05-01-2012. Asthma in the elderly: Risk factors and impact on physical function Annals of Allergy, Asthma and Immunology, 108 5, 305-310

Iossifova Y.;Reponen T.;Bernstein D.;Levin L.;Kalra H.;Campo P.;Villareal M.;Lockey J.;Hershey G.;LeMasters G. 05-01-2007. House dust (1-3)-?-D-glucan and wheezing in infants Allergy: European Journal of Allergy and Clinical Immunology, 62 5, 504-513

Kim H.;Levin L.;Lemasters G.;Villareal M.;Evans S.;Lockey J.;Khurana Hershey G.;Bernstein D. 04-01-2012. Validating childhood symptoms with physician-diagnosed allergic rhinitis Annals of Allergy, Asthma and Immunology, 108 4, 228-231

Kannan J.;Brokamp C.;Bernstein D.;Lemasters G.;Hershey G.;Villareal M.;Lockey J.;Ryan P. 03-01-2017. Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated wi Pediatric, Allergy, Immunology, and Pulmonology, 30 1, 31-38

Sucharew H.;Ryan P.;Bernstein D.;Succop P.;Khurana Hershey G.;Lockey J.;Villareal M.;Reponen T.;Grinshpun S.;Lemasters G. 03-01-2010. Exposure to traffic exhaust and night cough during early childhood: The CCAAPS birth cohort Pediatric Allergy and Immunology, 21 2 PART 1, 253-259

Codispoti C.;Lemasters G.;Levin L.;Reponen T.;Ryan P.;Biagini Myers J.;Villareal M.;Burkle J.;Evans S.;Lockey J.;Khurana Hershey G.;Bernstein D. 02-01-2015. Traffic pollution is associated with early childhood aeroallergen sensitization Annals of Allergy, Asthma and Immunology, 114 2, 126-133.e3

Ryan P.;LeMasters G.;Biswas P.;Levin L.;Hu S.;Lindsey M.;Bernstein D.;Lockey J.;Villareal M.;Khurana Hershey G.;Grinshpun S. 02-01-2007. A comparison of proximity and land use regression traffic exposure models and wheezing in infants Environmental Health Perspectives, 115 2, 278-284

Codispoti C.;Bernstein D.;Levin L.;Reponen T.;Ryan P.;Biagini Myers J.;Villareal M.;Burkle J.;Lummus Z.;Lockey J.;Khurana Hershey G.;Lemasters G. 01-01-2015. Early-life mold and tree sensitivity is associated with allergic eosinophilic rhinitis at 4 years of Annals of Allergy, Asthma and Immunology, 114 3, 193-198.e4

Amin P.;Levin L.;Epstein T.;Ryan P.;LeMasters G.;Khurana Hershey G.;Reponen T.;Villareal M.;Lockey J.;Bernstein D. 01-01-2014. Optimum Predictors of Childhood Asthma: Persistent Wheeze or the Asthma Predictive Index? Journal of Allergy and Clinical Immunology: In Practice, 2 6, 709-715.e2

Cheng G.;Smith A.;Levin L.;Epstein T.;Ryan P.;Lemasters G.;Khurana Hershey G.;Reponen T.;Villareal M.;Lockey J.;Bernstein D. 01-01-2014. Duration of day care attendance during infancy predicts asthma at the age of seven: The Cincinnati C Clinical and Experimental Allergy, 44 10, 1274-1281

Epstein T.;Lemasters G.;Bernstein D.;Ericksen M.;Martin L.;Ryan P.;Biagini Myers J.;Butsch Kovacic M.;Lindsey M.;He H.;Reponen T.;Villareal M.;Lockey J.;Bernstein C.;Khurana Hershey G. 01-01-2012. Genetic variation in small proline rich protein 2B as a predictor for asthma among children with ecz Annals of Allergy, Asthma and Immunology, 108 3,

Epstein T.;Ryan P.;Lemasters G.;Bernstein C.;Levin L.;Bernstein J.;Villareal M.;Bernstein D. 01-01-2012. Poor asthma control and exposure to traffic pollutants and obesity in older adults Annals of Allergy, Asthma and Immunology, 108 6,

Reponen T.;Lockey J.;Bernstein D.;Vesper S.;Levin L.;Khurana Hershey G.;Zheng S.;Ryan P.;Grinshpun S.;Villareal M.;Lemasters G. 01-01-2012. Infant origins of childhood asthma associated with specific molds Journal of Allergy and Clinical Immunology, 130 3,

Epstein T.;Bernstein D.;Levin L.;Khurana Hershey G.;Ryan P.;Reponen T.;Villareal M.;Lockey J.;Lemasters G. 01-01-2011. Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth co Journal of Pediatrics, 158 2,

Codispoti C.;Levin L.;LeMasters G.;Ryan P.;Reponen T.;Villareal M.;Burkle J.;Stanforth S.;Lockey J.;Khurana Hershey G.;Bernstein D. 01-01-2010. Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determina Journal of Allergy and Clinical Immunology, 125 5,

Iossifova Y.;Reponen T.;Ryan P.;Levin L.;Bernstein D.;Lockey J.;Hershey G.;Villareal M.;Lemasters G. 01-01-2009. Mold exposure during infancy as a predictor of potential asthma development Annals of Allergy, Asthma and Immunology, 102 2, 131-137

Schroer K.;Biagini Myers J.;Ryan P.;LeMasters G.;Bernstein D.;Villareal M.;Lockey J.;Reponen T.;Grinshpun S.;Khurana Hershey G. 01-01-2009. Associations between Multiple Environmental Exposures and Glutathione S-transferase P1 on Persistent Journal of Pediatrics, 154 3,

Smith A.M.;Bernstein D.I.;LeMasters G.K.;Huey N.L.;Ericksen M.;Villareal M.;Lockey J.;Khurana Hershey G.K. 01-01-2008. Environmental Tobacco Smoke and Interleukin 4 Polymorphism (C-589T) Gene: Environment Interaction In Journal of Pediatrics, 152 5,

Vesper S.;McKinstry C.;Haugland R.;Iossifova Y.;Lemasters G.;Levin L.;Khurana Hershey G.;Villareal M.;Bernstein D.;Lockey J.;Reponen T. 01-01-2007. Relative moldiness index as predictor of childhood respiratory illness Journal of Exposure Science and Environmental Epidemiology, 17 1, 88-94

Cho S.;Reponen T.;LeMasters G.;Levin L.;Huang J.;Meklin T.;Ryan P.;Villareal M.;Bernstein D. 01-01-2006. Mold damage in homes and wheezing in infants Annals of Allergy, Asthma and Immunology, 97 4, 539-545

White J.;Levin L.;Villareal M.;Murphy K.;Biagini R.;Wellinghoff L.;St. Clair H.;Bernstein D. 01-01-2005. Lack of correlation between regional pollen counts and percutaneous reactivity to tree pollen extrac Annals of Allergy, Asthma and Immunology, 94 2, 240-246

Lang D.;Visintainer P.;Howland W.;Stein M.;Villareal M. 01-01-2000. Survey of the extent and nature of care for adults and older adults by Allergy/Immunology practition Annals of Allergy, Asthma and Immunology, 85 2, 106-110