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ASPET Summer Undergraduate Research Fellowships

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Alexander Vinks

Contact Information

Peer Reviewed Publications

Chidambaran, Vidya; Ngamprasertwong, Pornswan; Vinks, Alexander A; Sadhasivam, Senthilkumar 2012. Pharmacogenetics and anesthetic drugs. Current clinical pharmacology, 7 2, 78-101

Fukuda, Tsuyoshi; Goebel, Jens; Cox, Shareen; Maseck, Denise; Zhang, Kejian; Sherbotie, Joseph R; Ellis, Eileen N; James, Laura P; Ward, Robert M; Vinks, Alexander A 2012. UGT1A9, UGT2B7, and MRP2 Genotypes Can Predict Mycophenolic Acid Pharmacokinetic Variability in Pediatric Kidney Transplant Recipients. Therapeutic drug monitoring, 34 6, 671-679

Hooper, David K; Fukuda, Tsuyoshi; Gardiner, Rhonda; Logan, Barbara; Roy-Chaudhury, Ashwini; Kirby, Cassie L; Vinks, Alexander A; Goebel, Jens 2012. Risk of tacrolimus toxicity in CYP3A5 nonexpressors treated with intravenous nicardipine after kidney transplantation. Transplantation, 93 8, 806-12

Ngamprasertwong, Pornswan; Vinks, Alexander A; Boat, Anne 2012. Update in Fetal Anesthesia for the Ex Utero Intrapartum Treatment (EXIT) Procedure. International anesthesiology clinics, 50 4, 26-40

Sherwin, Catherine M T; Sagcal-Gironella, Anna Carmela P; Fukuda, Tsuyoshi; Brunner, Hermine I; Vinks, Alexander A 2012. Development of population PK model with enterohepatic circulation for mycophenolic acid in patients with childhood-onset systemic lupus erythematosus. British journal of clinical pharmacology, 73 5, 727-40

Sherwin, Catherine M T; Saldaña, Shannon N; Bies, Robert R; Aman, Michael G; Vinks, Alexander A 2012. Population pharmacokinetic modeling of risperidone and 9-hydroxyrisperidone to estimate CYP2D6 subpopulations in children and adolescents. Therapeutic drug monitoring, 34 5, 535-44

Wiles, Jason R; Vinks, Alexander A; Akinbi, Henry 2012. Federal Legislation and the Advancement of Neonatal Drug Studies. The Journal of pediatrics, ,

Fukuda, Tsuyoshi; Brunner, Hermine I; Sagcal-Gironella, Anna Carmela P; Vinks, Alexander A 2011. Nonsteroidal anti-inflammatory drugs may reduce enterohepatic recirculation of mycophenolic acid in patients with childhood-onset systemic lupus erythematosus. Therapeutic drug monitoring, 33 5, 658-62

Fukuda, Tsuyoshi; Goebel, Jens; Thøgersen, Håvard; Maseck, Denise; Cox, Shareen; Logan, Barbara; Sherbotie, Joseph; Seikaly, Mouin; Vinks, Alexander A 2011. Inosine monophosphate dehydrogenase (IMPDH) activity as a pharmacodynamic biomarker of mycophenolic acid effects in pediatric kidney transplant recipients. Journal of clinical pharmacology, 51 3, 309-20

Merhar, Stephanie L; Schibler, Kurt R; Sherwin, Catherine M; Meinzen-Derr, Jareen; Shi, Jing; Balmakund, Tonya; Vinks, Alexander A 2011. Pharmacokinetics of levetiracetam in neonates with seizures. The Journal of pediatrics, 159 1, 152-154.e3

Sagcal-Gironella, Anna Carmela P; Fukuda, Tsuyoshi; Wiers, Kristina; Cox, Shareen; Nelson, Shannen; Dina, Blair; Sherwin, Catherine M T; Klein-Gitelman, Marisa S; Vinks, Alexander A; Brunner, Hermine I 2011. Pharmacokinetics and pharmacodynamics of mycophenolic acid and their relation to response to therapy of childhood-onset systemic lupus erythematosus. Seminars in arthritis and rheumatism, 40 4, 307-13

Sagcal-Gironella, Anna Carmela P; Sherwin, Catherine M T; Tirona, Rommel G; Rieder, Michael J; Brunner, Hermine I; Vinks, Alexander A 2011. Pharmacokinetics of prednisolone at steady state in young patients with systemic lupus erythematosus on prednisone therapy: an open-label, single-dose study. Clinical therapeutics, 33 10, 1524-36

Saldaña, Shannon N; Hooper, David K; Froehlich, Tanya E; Campbell, Kathleen M; Prows, Cynthia A; Sadhasivam, Senthilkumar; Nick, Todd G; Seid, Michael; Vinks, Alexander A; Glauser, Tracy A 2011. Characteristics of successful recruitment in prospective pediatric pharmacogenetic studies. Clinical therapeutics, 33 12, 2072-81

Sherwin, Catherine M T; Ding, Lili; Kaplan, Jennifer; Spigarelli, Michael G; Vinks, Alexander A 2011. Optimal study design for pioglitazone in septic pediatric patients. Journal of pharmacokinetics and pharmacodynamics, 38 4, 433-47

Sherwin, Catherine M T; Fukuda, Tsuyoshi; Brunner, Hermine I; Goebel, Jens; Vinks, Alexander A 2011. The evolution of population pharmacokinetic models to describe the enterohepatic recycling of mycophenolic acid in solid organ transplantation and autoimmune disease. Clinical pharmacokinetics, 50 1, 1-24

Glauser, Tracy A; Cnaan, Avital; Shinnar, Shlomo; Hirtz, Deborah G; Dlugos, Dennis; Masur, David; Clark, Peggy O; Capparelli, Edmund V; Adamson, Peter C 2010. Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy. The New England journal of medicine, 362 9, 790-9

Mehta, Parinda A; Vinks, Alexander A; Filipovich, Alexandra; Bleesing, Jack; Jodele, Sonata; Jordan, Michael B; Marsh, Rebecca; Tarin, Richard; Edwards, Stephanie; Fearing, Deborah; Lawrence, Julia; Davies, Stella M 2010. Alternate-day micafungin antifungal prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation: a pharmacokinetic study. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 16 10, 1458-62

Vargus-Adams, Jilda N; McMahon, Mary A; Michaud, Linda J; Bean, Judy; Vinks, Alexander A 2010. Pharmacokinetics of amantadine in children with impaired consciousness due to acquired brain injury: preliminary findings using a sparse-sampling technique. PM & R : the journal of injury, function, and rehabilitation, 2 1, 37-42

Pestian, John; Spencer, Malik; Matykiewicz, Pawel; Zhang, Kejian; Vinks, Alexander A; Glauser, Tracy 2009. Personalizing Drug Selection Using Advanced Clinical Decision Support. Biomedical informatics insights, 2 , 19-29

Prausa, S E; Fukuda, T; Maseck, D; Curtsinger, K L; Liu, C; Zhang, K; Nick, T G; Sherbotie, J R; Ellis, E N; Goebel, J; Vinks, A A 2009. UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients. Clinical pharmacology and therapeutics, 85 5, 495-500

Prows, Cynthia A; Nick, Todd G; Saldaña, Shannon N; Pathak, Sanjeev; Liu, Chunyan; Zhang, Kejian; Daniels, Zachary S; Vinks, Alexander A; Glauser, Tracy A 2009. Drug-metabolizing enzyme genotypes and aggressive behavior treatment response in hospitalized pediatric psychiatric patients. Journal of child and adolescent psychopharmacology, 19 4, 385-94

Cabovska, B; Cox, S L; Vinks, A A 2007. Determination of risperidone and enantiomers of 9-hydroxyrisperidone in plasma by LC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 852 1-2, 497-504

Vinks, Alexander A; van Rossem, Ronald N; Mathôt, Ron A A; Heijerman, Harry G M; Mouton, Johan W 2007. Pharmacokinetics of aztreonam in healthy subjects and patients with cystic fibrosis and evaluation of dose-exposure relationships using monte carlo simulation. Antimicrobial agents and chemotherapy, 51 9, 3049-55

Jiang, Zhengwen; Dragin, Nadine; Jorge-Nebert, Lucia F; Martin, Martha V; Guengerich, F Peter; Aklillu, Eleni; Ingelman-Sundberg, Magnus; Hammons, George J; Lyn-Cook, Beverly D; Kadlubar, Fred F; Saldana, Shannon N; Sorter, Michael; Vinks, Alexander A; Nassr, Nassr; von Richter, Oliver; Jin, Li; Nebert, Daniel W 2006. Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype. Pharmacogenetics and genomics, 16 5, 359-67

Mehta, Parinda; Vinks, Alexander; Filipovich, Alexandra; Vaughn, Gretchen; Fearing, Deborah; Sper, Christine; Davies, Stella 2006. High-dose weekly AmBisome antifungal prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation: a pharmacokinetic study. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 12 2, 235-40

Vinks, Alexander A; Den Hollander, Jan G; Overbeek, Shelley E; Jelliffe, Roger W; Mouton, Johan W 2003. Population pharmacokinetic analysis of nonlinear behavior of piperacillin during intermittent or continuous infusion in patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 47 2, 541-7

Vinks, Alexander A 2002. The application of population pharmacokinetic modeling to individualized antibiotic therapy. International journal of antimicrobial agents, 19 4, 313-22

Rogers, Christin C; Alloway, Rita R; Alexander, J Wesley; Cardi, Michael; Trofe, Jennifer; Vinks, Alexander A . Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study. Clinical transplantation, 22 3, 281-91

Sadhasivam, Senthilkumar; Krekels, Elke H J; Chidambaran, Vidya; Esslinger, Hope R; Ngamprasertwong, Pornswan; Zhang, Kejian; Fukuda, Tsuyoshi; Vinks, Alexander A . Morphine clearance in children: does race or genetics matter? Journal of opioid management, 8 4, 217-26

Williams, Michael T; Brown, Carrie A; Skelton, Matthew R; Vinks, Alexander A; Vorhees, Charles V . Absorption and clearance of +/-3,4-methylenedioxymethamphetamine from the plasma of neonatal rats. Neurotoxicology and teratology, 26 6, 849-56